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Diseases

Genetic and Rare Diseases Information Center (GARD)

Cryptogenic organizing pneumonia


Other Names for this Disease
  • COP
  • Idiopathic bronchiolitis obliterans organizing pneumonia
  • Idiopathic BOOP
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Overview

Cryptogenic organizing pneumonia (COP) is a form of idiopathic interstitial pneumonia characterized by lung inflammation and scarring that obstructs the small airways and air sacs of the lungs (alveoli).[1] Signs and symptoms may include flu-like symptoms such as cough, fever, malaise, fatigue and weight loss. COP often affects adults in midlife (40 to 60 years of age). The exact underlying cause of the condition is unknown (idiopathic). Treatment varies based on the severity of the condition but generally includes glucocorticoids.[2][3][4]
Last updated: 12/21/2015

References

  1. Harold R. Collard. Cryptogenic Organizing Pneumonia. Merck Manual. 2015; http://www.merckmanuals.com/home/lung-and-airway-disorders/interstitial-lung-diseases/cryptogenic-organizing-pneumonia.
  2. Cordier JF. Cryptogenic organizing pneumonia. Clin Chest Med. December 2004; 25(4):727-738.
  3. Talmadge E King, Jr, MD. Cryptogenic organizing pneumonia. UpToDate. December 2014; Accessed 7/16/2015.
  4. Bronchiolitis Obliterans Organizing Pneumonia. NORD. 2013; http://rarediseases.org/rare-diseases/bronchiolitis-obliterans-organizing-pneumonia/.
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Basic Information

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • The Merck Manual for health care professionals provides information on Cryptogenic organizing pneumonia.
  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Cryptogenic organizing pneumonia. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • COP
  • Idiopathic bronchiolitis obliterans organizing pneumonia
  • Idiopathic BOOP
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.