Best vitelliform macular dystrophy
Other Names for this Disease
- Best disease
- Best macular dystrophy
- Macular degeneration, polymorphic vitelline
- Vitelliform macular dystrophy type 2
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macular degeneration. It usually begins in childhood or adolescence, but age of onset and severity of vision loss can vary. Affected people first have normal vision, followed by decreased central visual acuity and distorted vision (metamorphopsia). Peripheral vision is not affected. BVMD is usually inherited in an autosomal dominant manner, but autosomal recessive inheritance has been reported. The condition is typically caused by mutations in the BEST1 gene; in a few cases the cause is unknown. Treatment is symptomatic and involves the use of low vision aids.Best vitelliform macular dystrophy (BVMD) is a slowly progressive form of
Last updated: 2/13/2015
- Ian M MacDonald and Thomas Lee. Best Vitelliform Macular Dystrophy. GeneReviews. December 12, 2013; http://www.ncbi.nlm.nih.gov/books/NBK1167/.
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- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
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