Best vitelliform macular dystrophy
Other Names for this Disease
- Best disease
- Best macular dystrophy
- Macular degeneration, polymorphic vitelline
- Vitelliform macular dystrophy type 2
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macular degeneration. It usually begins in childhood or adolescence, but age of onset and severity of vision loss can vary. Affected people first have normal vision, followed by decreased central visual acuity and distorted vision (metamorphopsia). Peripheral vision is not affected. BVMD is usually inherited in an autosomal dominant manner, but autosomal recessive inheritance has been reported. The condition is typically caused by mutations in the BEST1 gene; in a few cases the cause is unknown. Treatment is symptomatic and involves the use of low vision aids.Best vitelliform macular dystrophy (BVMD) is a slowly progressive form of
Last updated: 2/13/2015
- Ian M MacDonald and Thomas Lee. Best Vitelliform Macular Dystrophy. GeneReviews. December 12, 2013; http://www.ncbi.nlm.nih.gov/books/NBK1167/.
- Genetics Home Reference (GHR) contains information on Best vitelliform macular dystrophy. This website is maintained by the National Library of Medicine.
- The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Best vitelliform macular dystrophy. Click on the link to view a sample search on this topic.