Dysplasia epiphysealis hemimelica
Other Names for this Disease
- Trevor disease
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 Early diagnosis and treatment are necessary to prevent joint dysfunction and deformity and may be surgical or non-surgical depending on the location and the symptoms. Due to the progressive nature of this disorder and the chance of worsening deformity, patients should be followed until skeletal maturity. The cause of dysplasia epiphysealis hemimelica is not known.Dysplasia epiphysealis hemimelica (DEH), or Trevor's disease, is a rare condition that most commonly affects the epiphysis (the end) of long bones in children.
Last updated: 5/10/2011
- Wenger DR, Adamczk MJ. Evaluation, imaging, histology and operative treatment for dysplasia epiphysealis hemimelica (Trevor disease) of the acetabulum: a case report and review. Iowa Orthop J. 2005; http://www.ncbi.nlm.nih.gov/pubmed/16089075. Accessed 5/10/2011.
- Glick R, Khaldi L, Ptaszynski K, Steiner GC. Dysplasia epiphysealis hemimelica (Trevor disease): a rare developmental disorder of bone mimicking osteochondroma of long bones. Hum Pathol. 2007; http://www.ncbi.nlm.nih.gov/pubmed/17490719. Accessed 5/10/2011.
- Rosero VM, Kiss S, Terebessy T, Kollo K, Szoke G. Dysplasia epiphysealis hemimelica (Trevor's disease): 7 of our own cases and a review of the literature. Acta Orthop. 2007; http://www.ncbi.nlm.nih.gov/pubmed/18236195. Accessed 5/10/2011.
- Douira-Khomsi W, Louati H, Mormech Y, et al.. Dysplasia epiphysealis hemimelica: a report of four cases. Foot Ankle Surg. 2011; http://www.ncbi.nlm.nih.gov/pubmed/21276564. Accessed 5/10/2011.
- Smith EL, Raney EM, Matzkin EG, Fillman RR, Yandow SM. Trevor's disease: the clinical manifestations and treatment of dysplasia epiphysealis hemimelica. J Pediatr Orthop B. 2007; http://www.ncbi.nlm.nih.gov/pubmed/17527110. Accessed 5/10/2011.
- The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Dysplasia epiphysealis hemimelica. Click on the link to view a sample search on this topic.