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Diseases

Genetic and Rare Diseases Information Center (GARD)

Epidermolysis bullosa simplex, generalized


Other Names for this Disease
  • EBS, generalized
  • Generalized EBS
  • Epidermolysis bullosa simplex, Koebner type
  • EBS-K
  • Epidermolysis bullosa simplex, generalized non-Dowling-Meara
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Treatment

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How might epidermolysis bullosa simplex be treated?

There is no cure for epidermolysis bullosa simplex and there is no known treatment proven to completely control all of the symptoms. However, many complications can be lessened or avoided through early intervention. Individuals with milder forms of the disease have minimal symptoms and may require little or no treatment. In all cases, treatment is directed towards the symptoms and is largely supportive. This care should focus on prevention of infection, protection of the skin against trauma, attention to nutritional deficiencies and dietary complications, minimization of deformities and contractures, and the need for psychological support for the patient and other family members.[1] 

Detailed information regarding prevention of blisters, care of blisters and infections, and management of nutritional problems can be accessed through the National Institute of Arthritis and Musculoskeletal and Skin  Diseases (NIAMS) and article from the eMedicine journal.
Last updated: 5/6/2010

References
  1. EB Simplex: Koebner Subtype of EB Simplex. Dystrophic Epidermolysis Bullosa Research Association of America (DebRA). http://www.debra.org/simplex#koebner. Accessed 6/10/2015.


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Other Names for this Disease
  • EBS, generalized
  • Generalized EBS
  • Epidermolysis bullosa simplex, Koebner type
  • EBS-K
  • Epidermolysis bullosa simplex, generalized non-Dowling-Meara
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.