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Diseases

Genetic and Rare Diseases Information Center (GARD)

Olfactory neuroblastoma


Other Names for this Disease
  • Esthesioneuroblastoma
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Overview

Olfactory neuroblastoma is a rare cancer of the upper part of the nasal cavity called the cribiform plate, which is a bone deep in the skull between the eyes, and above the ethmoid sinuses. It accounts for about 5% of all cancers of the nasal cavity and paranasal sinuses. It develops in nerve tissue associated with the sense of smell (olfactory nerve). It can occur at any age, but typically is found in adulthood.[1][2][3] Symptoms may be nonspecific and include a blockage of the nasal passageways due to the tumor, facial pain, runny nose, and nosebleeds. Treatment usually includes surgery to remove the tumor, radiation therapy, and sometimes chemotherapy.[2]
Last updated: 6/29/2016

References

  1. Nasal Cavity and Paranasal Sinuses Cancer. American Cancer Society. 3/2/2015; http://www.cancer.org/cancer/nasalcavityandparanasalsinuscancer/detailedguide/nasal-cavity-and-paranasal-sinuses-cancer-what-is-nasal-paranasal.
  2. Carl Snyderman, Derrick Lin, Bruce E Brockstein, Robert Foote, Jerome B Taxy. Olfactory neuroblastoma (esthesioneuroblastoma). UpToDate. Jan 8, 2016; http://www.uptodate.com/contents/olfactory-neuroblastoma-esthesioneuroblastoma.
  3. Michael Somenek. Esthesioneuroblastoma. Medscape. April 14, 2015; http://emedicine.medscape.com/article/278047.
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Basic Information

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Olfactory neuroblastoma. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Esthesioneuroblastoma
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.