Other Names for this Disease
- Idiopathic dilated cardiomyopathy
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 It is the most common type of cardiomyopathy and typically affects those aged 20 to 60. The left ventricle of affected individuals becomes enlarged (dilated) and cannot pump blood to the body with as much force as a healthy heart can. The heart muscle also has difficulty contracting normally, which can lead to irregular heartbeats (arrhythmia), blood clots, or sudden death. Over time, the heart becomes weaker and heart failure can occur. While the cause of dilated cardiomyopathy is often unknown (idiopathic), some cases are acquired and roughly half are inherited or familial. Familial dilated cardiomyopathy is most often inherited in an autosomal dominant pattern. Mutations in the TTN gene are found in approximately 20 percent of cases of familial dilated cardioyopathy.Dilated cardiomyopathy is a disease of the heart muscle which primarily affects the heart's main pumping chamber, the left ventricle.
Last updated: 3/29/2013
- Dilated cardiomyopathy. MayClinic.com. September 2011; http://www.mayoclinic.com/print/dilated-cardiomyopathy/DS01029/METHOD=print&DSECTION=all. Accessed 9/29/2011.
- What is Cardiomyopathy?. National Heart, Lung and Blood Institute (NHLBI). January 2011; http://www.nhlbi.nih.gov/health/health-topics/topics/cm/types.html. Accessed 9/29/2011.
- Familial dilated cardiomyopathy. Genetic Home Reference. http://ghr.nlm.nih.gov/condition/familial-dilated-cardiomyopathy. Accessed 6/4/2015.
- MayoClinic.com provides information about dilated cardiomyopathy. Click on the above link to access this information.
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
- The Merck Manuals Online Medical Library provides information on this condition for patients and caregivers.
- The National Heart, Lung, and Blood Institute (NHLBI) has information on this topic. NHLBI is part of the National Institutes of Health and supports research, training, and education for the prevention and treatment of heart, lung, and blood diseases.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Dilated cardiomyopathy. Click on the link to view a sample search on this topic.