Factor V deficiency
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 The reduced amount of factor V leads to episodes of abnormal bleeding that range from mild to severe. Factor V deficiency is inherited in an autosomal recessive manner, which means that both copies of the F5 gene in each cell have mutations.Factor V deficiency is an inherited blood disorder that involves abnormal blood clotting (coagulation). This disorder is caused by the deficiency of a blood protein called factor V.
Last updated: 7/22/2013
- Matsui W. Factor V deficiency. MedlinePlus Web site. May 3, 2006; http://www.nlm.nih.gov/medlineplus/ency/article/000550.htm. Accessed 3/24/2008.
- Factor V deficiency. National Hemophilia Foundation Web site. http://www.hemophilia.org/NHFWeb/MainPgs/MainNHF.aspx?menuid=186&contentid=409&rptname=bleeding. Accessed 3/24/2008.
- Genetics Home Reference contains information on Factor V deficiency. This website is maintained by the National Library of Medicine.
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
- The National Heart, Lung, and Blood Institute (NHLBI) can provide information on this topic. You can reach them by calling 301-592-8573 or by E-mail at firstname.lastname@example.org
- The National Hemophilia Foundation has an information page on factor V deficiency.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Factor V deficiency. Click on the link to view a sample search on this topic.