Medullary sponge kidney
Other Names for this Disease
- Cacchi Ricci disease
- Precalyceal canalicular ectasia
- Cacchi-Ricci syndrome
- Sponge kidney
- Cystic dilatation of renal collecting tubes
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Medullary sponge kidney (MSK) is a birth defect of the tubules-tiny tubes inside the kidneys. In a normal kidney, urine flows through these tubules as it is being formed. In MSK, tiny sacs called cysts form in the medulla-the inner part of the kidney-creating a sponge-like appearance. The cysts keep urine from flowing freely through the tubules. MSK is present at birth but symptoms typically do not occur until adulthood. Problems caused by MSK, include blood in the urine, kidney stones, and urinary tract infections. MSK rarely leads to more serious problems, such as total kidney failure.
Last updated: 10/10/2012
- Medullary Sponge Kidney. National Kidney and Urologic Diseases Information Clearinghouse. September 2012; http://kidney.niddk.nih.gov/kudiseases/pubs/medullaryspongekidney/. Accessed 10/10/2012.
- The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC), part of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), conducts and supports research on a broad spectrum of diseases affecting public health. Click on the link to view information on this topic.
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- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
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