Other Names for this Disease
- Osteochondrosis of the metatarsal head, usually the second
- Freiberg's infraction
- Kohler's second disease
- Second metatarsal osteochondrosis
- Freiberg-Kohler syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.
metatarsal (the long bones of the foot). Although people of all ages can be affected by this condition, Freiberg's disease is most commonly diagnosed during adolescence through the second decade of life. Common signs and symptoms include pain and stiffness in the front of the foot, which often leads to a limp. Affected people may also experience swelling, limited range of motion, and tenderness of the affected foot. Symptoms are generally triggered by weight-bearing activities, including walking. The exact underlying cause of Freiberg's disease is currently unknown. Treatment depends on many factors, including the severity of condition; the signs and symptoms present; and the age of the patient.Freiberg's disease is rare condition that primarily affects the second or third
Last updated: 5/14/2015
- Shayne D Fehr, MD, FAAP. Freiberg Disease. Medscape Reference. March 2015; http://emedicine.medscape.com/article/1236085-overview.
- Shane A, Reeves C, Wobst G, Thurston P. Second metatarsophalangeal joint pathology and freiberg disease. Clin Podiatr Med Surg. July 2013; 30(3):313-325.
- Cerrato RA. Freiberg's disease. Foot Ankle Clin. December 2011; 16(4):647-658.
- The Merck Manual provides information on this condition for patients and caregivers.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Merck Manual for health care professionals provides information on Freiberg's disease.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Freiberg's disease. Click on the link to view a sample search on this topic.