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Diseases

Genetic and Rare Diseases Information Center (GARD)

Acquired fructose intolerance


Other Names for this Disease
  • Fructose malabsorption
  • Intestinal fructose intolerance
  • Dietary fructose intolerance
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Overview

Acquired fructose intolerance is a condition in which the body can not properly absorb the sugar, fructose. As a result, affected people may experience gastrointestinal symptoms, such as gas, abdominal pain, bloating and/or diarrhea, depending on the quantity of fructose consumed and the presence of other sugars ingested with it. Gastrointestinal symptoms related to acquired fructose intolerance appear to be more common in people who have an underlying functional bowel disorder such as irritable bowel syndrome.[1][2] The underlying cause of the condition is poorly understood. It is distinct from the rare, genetic form of fructose intolerance (called hereditary fructose intolerance), which usually develops earlier in life and often affects more than one family member. Acquired fructose intolerance is generally managed with dietary modifications.[3]
Last updated: 4/1/2016

References

  1. Joel B Mason, MD; Vladan Milovic, MD, PhD. Overview of the treatment of malabsorption. UpToDate. April 2014;
  2. Ebert K, Witt H. Fructose malabsorption. Mol Cell Pediatr. December 2016; 3(1):10.
  3. Bonfrate L, Krawczyk M, Lembo A, Grattagliano I, Lammert F, Portincasa P. Effects of dietary education, followed by a tailored fructose-restricted diet in adults with fructose malabsorption. Eur J Gastroenterol Hepatol. July 2015; 27(7):785-796.
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In Depth Information

  • PubMed is a searchable database of medical literature and lists journal articles that discuss Acquired fructose intolerance. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Fructose malabsorption
  • Intestinal fructose intolerance
  • Dietary fructose intolerance
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.