Intestinal pseudoobstruction neuronal chronic idiopathic X-linked
Other Names for this Disease
- Congenital idiopathic intestinal pseudoobstruction
- CIIP X-linked
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FLNA gene, other genes or are secondary to other conditions. It may be inherited in some cases. Intestinal pseudoobstruction neuronal chronic idiopathic X-linked is caused by alterations (mutations) in the FLNA gene which is located in the X chromosome. There is no specific treatment but several medications and procedures may be used to treat the symptoms.Intestinal pseudo-obstruction is a condition characterized by impairment of the muscle contractions that move food through the digestive tract. The condition may arise from abnormalities of the gastrointestinal muscles themselves (myogenic) or from problems with the nerves that control the muscle contractions (neurogenic). When intestinal pseudo-obstruction occurs by itself, it is called primary or idiopathic (unknown cause) intestinal pseudo-obstruction. The disorder can also develop as a complication of another medical condition; in these cases, it is called secondary intestinal pseudo-obstruction. Individuals with this condition have symptoms that resemble those of an intestinal blockage (obstruction) but without any obstruction. It may be acute or chronic and is characterized by the presence of dilation of the bowel on imaging. The causes may be unknown or due to alterations (mutations) in the
Last updated: 7/17/2015
- Intestinal pseudo-obstruction. Genetics Home Reference. October, 2010; http://ghr.nlm.nih.gov/condition/intestinal-pseudo-obstruction#definition. Accessed 7/17/2015.
- Camilleri M. Chronic intestinal pseudo-obstruction. UpToDate. July 29, 2013; http://www.uptodate.com/contents/chronic-intestinal-pseudo-obstruction. Accessed 7/17/2015.
- Angkathunyakul N, Treepongkaruna S, Molagool S & Ruangwattanapaisarn N. Abnormal layering of muscularis propria as a cause of chronic intestinal pseudo-obstruction: A case report and literature review. World J Gastroenterol. June 14, 2015; 21(22):7059-7064. http://www-ncbi-nlm-nih-gov.ezproxy.nihlibrary.nih.gov/pmc/articles/PMC4462749/. Accessed 7/17/2015.
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- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
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