Tylosis with esophageal cancer
Other Names for this Disease
- Keratosis palmoplantaris with esophageal cancer
- Howel-Evans syndrome
- Keratosis palmaris et plantaris with esophageal cancer
- Howell-Evans syndrome
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Affected individuals may have periodic endoscopic and oral cavity evaluations by a gastroentrologist to detect esophageal cancer. For the palmoplantar keratoderma, a dermatologist may recommend oral retinoids such as etretinate, isotretinoin, and acitretin. Topical therapies may include soaking in salt water and then gentle removal of dead tissue (debridement) and 50% propylene glycol in water under plastic dressing overnight weekly.
Last updated: 1/18/2013
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