Megalencephalic leukoencephalopathy with subcortical cysts
- Leukoencephalopathy with swelling and cysts
- Megalencephalic leukodystrophy
- Megalencephaly - cystic leukodystrophy
- Megalencephaly-cystic leukodystrophy
Your QuestionI have a daughter with megalencephalic leukoencephalopathy with subcortical cysts. Can I expect to have a healthy baby in the next pregnancy? Who can I talk to about this?
We have identified the following information that we hope you find helpful. If you still have questions, please contact us.
Questions on this page
- What is megalencephalic leukoencephalopathy with subcortical cysts (MLC)?
- What causes megalencephalic leukoencephalopathy with subcortical cysts (MLC)?
- What is autosomal recessive inheritance?
I have one child with megalencephalic leukoencephalopathy with subcortical cysts. Can I expect to have a healthy baby in my next pregnancy?
Some people with MLC do not have detectable mutations in this gene. In these cases (about 25%) the cause of their condition is unknown. It is possible that there are genes other than MCL1 involved in causing MLC that have yet to be identified.
The following online resources can also help you find genetics professionals in your community:
- GeneTests - A searchable directory of US and international genetics and prenatal diagnosis clinics. Go to the following link and click on 'Clinic Directory' to find a genetic service close to you.
- American Society of Medical Genetics – A membership directory of genetics specialists around the world.
- Megalencephalic leukoencephalopathy with subcortical cysts. Genetics Home Reference. 2008; http://ghr.nlm.nih.gov/condition=megalencephalicleukoencephalopathywithsubcorticalcysts. Accessed 6/3/2009.
- What are the different ways in which a genetic condition can be inherited?. Genetics Home Reference Web site. September 23, 2013; http://ghr.nlm.nih.gov/handbook/inheritance/inheritancepatterns. Accessed 9/24/2013.