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Diseases

Genetic and Rare Diseases Information Center (GARD)

Chromosome 10q deletion


Other Names for this Disease
  • Deletion 10q
  • Monosomy 10q
  • 10q deletion
  • 10q monosomy
  • Partial monosomy 10q
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Overview

Chromosome 10q deletion is a chromosome abnormality that occurs when there is a missing copy of the genetic material located on the long arm (q) of chromosome 10. The severity of the condition and the signs and symptoms depend on the size and location of the deletion and which genes are involved. Features that often occur in people with chromosome 10q deletion include developmental delay, intellectual disability, behavioral problems, and distinctive facial features.[1] Most cases are not inherited, but people can pass the deletion on to their children. Treatment is based on the signs and symptoms present in each person.
Last updated: 12/9/2015

References

  1. Yatsenko SA1, Kruer MC, Bader PI, Corzo D, Schuette J, Keegan CE, Nowakowska B, Peacock S, Cai WW, Peiffer DA, Gunderson KL, Ou Z, Chinault AC, Cheung SW. Identification of critical regions for clinical features of distal 10q deletion syndrome. Clin Genet. July 2009; 76(1):54-62.
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Basic Information

In Depth Information

  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Chromosome 10q deletion. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Deletion 10q
  • Monosomy 10q
  • 10q deletion
  • 10q monosomy
  • Partial monosomy 10q
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.