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 It is mainly characterized by swelling of the lip with hyperplasia of the salivary glands; secretion of a clear, thick mucus; and variable inflammation. Enlargement and chronic exposure of the mucous membrane on the lower lip becomes affected by the environment, leading to erosion, ulceration, crusting, and, occasionally, infection. Cheilitis glandularis is more common in adult males, although cases have been described in women and children. In Caucasians, it is associated with a relatively high incidence of squamous cell carcinoma of the lip. Although there may be a genetic susceptibility, no definitive cause has been established. Treatment may include surgical excision by vermilionectomy (sometimes called a lip shave), but treatment varies for each individual.Cheilitis glandularis is a rare inflammatory disorder of the lip.
Last updated: 9/30/2015
- Ellen Eisenberg. Cheilitis Glandularis. Medscape Reference. March 6, 2014; http://emedicine.medscape.com/article/1078725-overview. Accessed 9/30/2015.
- Lourenco S, Nico M. Cheilitis glandularis. Orphanet. January 2015; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=1221. Accessed 9/30/2015.
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- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
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- Kids Skin Health, a American Academy of Dermatology's web site, provides kids, teens, and parents with information on skin conditions. Click on Kids Skin Health to access this Web site.