Familial pemphigus vulgaris
Other Names for this Disease
- Pemphigus vulgaris
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pemphigus vulgaris within a family. Pemphigus vulgaris is a rare autoimmune condition that is characterized by blisters and sores on the skin and mucus membranes. Although the exact cause of familial pemphigus vulgaris is unknown, autoimmune conditions generally occur when the body's immune system mistakenly attacks healthy tissue (in this case, the skin and mucus membranes). Most cases of pemphigus vulgaris occur sporadically in people with no family history of the condition; however, rare reports exist of "familial" cases which affect more than one member of a single family. In these cases, the underlying genetic cause is unknown, although an association between pemphigus vulgaris and certain HLA antigens has been identified. Treatment generally includes medications and other strategies to decrease blister formation, prevent infections and promote healing.Familial pemphigus vulgaris refers to a cluster of
Last updated: 12/17/2015
- Bassam Zeina, MD, PhD. Pemphigus Vulgaris. Medscape Reference. October 2015; http://emedicine.medscape.com/article/1064187-overview.
- Pemphigus vulgaris. DermNet NZ. April 2015; http://www.dermnetnz.org/immune/pemphigus-vulgaris.html.
- PEMPHIGUS VULGARIS, FAMILIAL. OMIM. August 2012; http://www.omim.org/entry/169610.
- DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
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- PubMed is a searchable database of medical literature and lists journal articles that discuss Familial pemphigus vulgaris. Click on the link to view a sample search on this topic.