Other Names for this Disease
- Cronkhite-Canada syndrome
- Gastrointestinal polyposis - ectodermal changes
- Gastrointestinal polyposis - skin pigmentation - alopecia - fingernail changes
- Polyposis skin pigmentation alopecia fingernail changes
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colon polyps, unhealthy looking (dystrophic) nails, hair loss (alopecia), darkening skin (such as on the hands, arms, neck and face), diarrhea, weight loss, stomach pain, and/or excess fluid accumulation in arms and legs (peripheral edema). The cause of the condition is not known. Treatment aims to control symptoms and provide adequate nutrition.Cronkhite-Canada syndrome is a rare gastrointestinal disorder characterized by widespread
Last updated: 5/31/2015
- Kao KT, Patel JK, Pampati V. Gastroenterol Res Pract. Epub 2009 Aug 25; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732131/?tool=pubmed. Accessed 5/31/2015.
- Serwin AB. Cronkhite-Canada syndrome. eMedicine. October 23, 2014; http://emedicine.medscape.com/article/1096789-overview. Accessed 5/31/2015.
- Cronkhite-Canada Syndrome. National Organization for Rare Disorders (NORD). 2005; http://rarediseases.org/rare-diseases/cronkhite-canada-syndrome/. Accessed 5/31/2015.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Cronkhite-Canada disease. Click on the link to view a sample search on this topic.
- Kopácová M, Urban O, Cyrany J et al. Cronkhite-Canada Syndrome: Review of the Literature. Gastroenterol Res Pract. 2013;2013:856873.