Other Names for this Disease
- Polyposis skin pigmentation alopecia fingernail changes
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colon polyps, unhealthy looking (dystrophic) nails, hair loss (alopecia), darkening skin (such as on the hands, arms, neck and face), diarrhea, weight loss, stomach pain, and/or excess fluid accumulation in arms and legs (peripheral edema). The cause of the condition is not known. Treatment aims to control symptoms and provide adequate nutrition.Cronkhite-Canada syndrome is a rare gastrointestinal disorder characterized by widespread
Last updated: 5/31/2015
- Kao KT, Patel JK, Pampati V. Gastroenterol Res Pract. Epub 2009 Aug 25; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732131/?tool=pubmed. Accessed 5/31/2015.
- Serwin AB. Cronkhite-Canada syndrome. eMedicine. October 23, 2014; http://emedicine.medscape.com/article/1096789-overview. Accessed 5/31/2015.
- Cronkhite-Canada Syndrome. National Organization for Rare Disorders (NORD). 2005; http://rarediseases.org/rare-diseases/cronkhite-canada-syndrome/. Accessed 5/31/2015.
- The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Cronkhite-Canada disease. Click on the link to view a sample search on this topic.
- Kopácová M, Urban O, Cyrany J et al. Cronkhite-Canada Syndrome: Review of the Literature. Gastroenterol Res Pract. 2013;2013:856873.