Familial prostate cancer
Other Names for this Disease
- Hereditary prostate cancer
- Prostate cancer, familial
- Prostate cancer, hereditary
sporadically in people with no family history of the condition. However, approximately 5% to 10% of prostate cancer cases are believed to be primarily caused by a genetic predisposition to the condition. In many families, the underlying genetic cause is unknown; however, some of these cases are caused by changes (mutations) in the BRCA1, BRCA2, HOXB13, or several other genes. Other cases are likely due to a combination of gene(s) and other shared factors such as environment and lifestyle. High-risk cancer screening at an earlier age is typically recommended in men who have an increased risk for prostate cancer based on personal and/or family histories.Familial prostate cancer is a cluster of prostate cancer within a family. Most cases of prostate cancer occur
Last updated: 12/7/2015
- Genetics of Prostate Cancer–for health professionals (PDQ®). National Cancer Institute. November 2015; http://www.cancer.gov/types/prostate/hp/prostate-genetics-pdq.
- Prostate Cancer. Genetics Home Reference. April 2015; http://ghr.nlm.nih.gov/condition/prostate-cancer.
- You can obtain information on this topic from the Centers for Disease Control and Prevention (CDC). The CDC is recognized as the lead federal agency for developing and applying disease prevention and control, environmental health, and health promotion and education activities designed to improve the health of the people of the United States.
- Genetics Home Reference (GHR) contains information on Familial prostate cancer. This website is maintained by the National Library of Medicine.
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- The National Human Genome Research Institute's (NHGRI) mission encompasses a broad range of studies aimed at understanding the structure and function of the human genome and its role in health and disease. Click on the link to view the information page on this topic.
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- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
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