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Diseases

Genetic and Rare Diseases Information Center (GARD)

Shapiro syndrome


Other Names for this Disease
  • Shapiro's syndrome
  • Recurrent spontaneous hypothermia with hypoplasia of the corpus callosum
  • Spontaneous periodic hypothermia syndrome
  • Spontaneous recurrent hypothermia syndrome
  • Spontaneous periodic hypothermia
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Treatment

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What treatment options have been attempted for Shapiro syndrome?

Evaluating effective treatment options for Shapiro syndrome can be difficult because of the limited number of diagnosed cases, the periodic nature of the disease, and other factors. Nonetheless, the following have been attempted and have resulted in varying responses: anticonvulsants, clonidine, cyproheptadine, glycopyrrolate, bromocriptine, chlorpromazine, or sympathectomy.[1] It is recommended that treatment options be discussed with a health care provider. Only a patient's health care provider can determine the appropriate course of treatment.
Last updated: 7/13/2009

References
  1. Dundar NL, Boz A, Duman O, Aydin F, Haspolat S. Spontaneous Periodic Hypothermia and Hyperhidrosis. Pediatr Neurol. 2008;


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Other Names for this Disease
  • Shapiro's syndrome
  • Recurrent spontaneous hypothermia with hypoplasia of the corpus callosum
  • Spontaneous periodic hypothermia syndrome
  • Spontaneous recurrent hypothermia syndrome
  • Spontaneous periodic hypothermia
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.