Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Short-chain acyl-CoA dehydrogenase deficiency


Other Names for this Disease
  • SCAD deficiency
  • ACADS deficiency
  • SCADH deficiency
  • Lipid-storage myopathy secondary to short-chain acyl-CoA dehydrogenase deficiency
  • Short-chain acyl-coenzyme A dehydrogenase deficiency
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

Newline Maker

How might short-chain acyl-CoA dehydrogenase (SCAD) deficiency be treated?

Treatment of short-chain acyl-CoA dehydrogenase (SCAD) deficiency usually consists of avoidance of fasting and a low fat diet. Supplemental carnitine may be recommended for some affected children during acute crises. Episodes of acute metabolic acidosis may be treated with intravenous hydration with a solution containing 10% glucose which can reestablish an anabolic state. This can be followed by reintroduction of the patient's usual diet.[1]
Last updated: 2/5/2016

References
  1. Jerry Vockley, MD, PhD. Short-Chain Acyl CoA Dehydrogenase Deficiency (SCAD). National Organization for Rare Disorders (NORD). 2013; http://rarediseases.org/rare-diseases/short-chain-acyl-coa-dehydrogenase-deficiency-scad/.


GARD Video Tutorial

  • Finding Treatment Information - A video developed by GARD Information Specialists that explains how you can find information about treatment for a rare disease.

    Finding Treatment Information

Management Guidelines

  • GeneReviews provides current, expert-authored, peer-reviewed, full-text articles describing the application of genetic testing to the diagnosis, management, and genetic counseling of patients with specific inherited conditions.

Clinical Trials & Research for this Disease

  • Orphanet lists European clinical trials, research studies, and patient registries enrolling people with this condition. 
  • The Research Portfolio Online Reporting Tool (RePORT) provides access to reports, data, and analyses of research activities at the National Institutes of Health (NIH), including information on NIH expenditures and the results of NIH-supported research. Although these projects may not conduct studies on humans, you may want to contact the investigators to learn more. To search for studies, enter the disease name in the "Text Search" box. Then click "Submit Query".
Other Names for this Disease
  • SCAD deficiency
  • ACADS deficiency
  • SCADH deficiency
  • Lipid-storage myopathy secondary to short-chain acyl-CoA dehydrogenase deficiency
  • Short-chain acyl-coenzyme A dehydrogenase deficiency
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.