Spastic paraplegia 11
Other Names for this Disease
- Hereditary spastic paraplegia mental impairment and thin corpus callosum
- Autosomal recessive spastic paraplegia type 11
- Hereditary spastic paraplegia 11
- Nakamura Osame syndrome
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Care for SPG11 is usually managed by a team including a primary care physician, neurologist, genetics professional (geneticist and/or genetic counselor), physical therapist, social worker, and psychologist. Treatment is focused on alleviating symptoms and may include:
- Medications for leg spasticity (antispastic drugs)
- Medications to assist in bladder control (anticholinergic antispasmodic drugs)
- Regular physician therapy
- Botulinum toxin and intrathecal baclofen for severe spasticity
Last updated: 5/31/2016
- Stevanin G, Durr A, Brice A. Spastic paraplegia 11. GeneReviews. January 31, 2013; https://www.ncbi.nlm.nih.gov/books/NBK1210/.
- GeneReviews provides current, expert-authored, peer-reviewed, full-text articles describing the application of genetic testing to the diagnosis, management, and genetic counseling of patients with specific inherited conditions.