Spinal muscular atrophy type 2
Other Names for this Disease
- Chronic infantile spinal muscular atrophy
- Chronic spinal muscular atrophy
- Dubowitz disease
- Intermediate spinal muscular atrophy
- Muscular atrophy, spinal, infantile chronic form
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Your QuestionAre there any other diseases or conditions that have similar symptoms to SMA, or mimic the symptoms of SMA?
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The main features of spinal muscular atrophy (SMA) include progressive muscle weakness and poor muscle tone (hypotonia), which may be present in a variety of conditions. (For a more detailed explanation of the signs and symptoms of SMA click here.) The following conditions are part of the differential diagnosis for people with symptoms of SMA because they share similar features:
- Prader-Willi syndrome and other chromosome abnormalities
- Pompe disease
- Congenital myasthenia
- Congenital myopathies (such as nemaline myopathy, central core disease, and myotubular myopathy)
- Myotonic dystrophy
- Congenital muscular dystrophy
- Duchenne muscular dystrophy
- Becker muscular dystrophy
- Kennedy's disease
- Amyotrophic lateral sclerosis
- Zellweger syndrome spectrum
- Peripheral neuropathies, including Guillain-Barré syndrome
- Central nervous system abnormalities
- Trauma to the spinal cord
Last updated: 3/25/2015
- Thomas W Prior, PhD, FACMG and Barry S Russman, MD. Spinal Muscular Atrophy. GeneReviews. November 2013; http://www.ncbi.nlm.nih.gov/books/NBK1352/.
- Spinal Muscular Atrophy. NORD. 2012; https://www.rarediseases.org/rare-disease-information/rare-diseases/byID/1135/viewAbstract.