Familial stomach cancer
Other Names for this Disease
- Stomach carcinoma, familial
- Familial stomach carcinoma
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sporadically in people with little to no family history of the condition; however, approximately 10% of stomach cancer is considered "familial." Although the underlying cause of some familial cases is unknown, genetic changes (mutations) are identified in a subset of people affected by gastric cancer. Hereditary cancer syndromes associated with a predisposition to gastric cancer include hereditary diffuse gastric cancer, Lynch syndrome, Li-Fraumeni syndrome, familial adenomatous polyposis, and Peutz-Jeghers syndrome. In other families, the cluster of stomach cancers may be due to a combination of gene(s) and/or other shared factors such as environment and lifestyle. Depending on the estimated risk, high-risk cancer screening and/or prophylactic surgeries are typically recommended in people who have an increased risk for stomach cancer based on their personal and/or family histories.Familial stomach cancer is a cluster of stomach cancer within a family. Most cases of stomach cancer occur
Last updated: 12/16/2015
- Cabebe EC. Gastric Cancer. Medscape Reference. November, 2015; http://emedicine.medscape.com/article/278744-overview.
- Colvin H, Yamamoto K, Wada N, Mori M. Hereditary Gastric Cancer Syndromes. Surg Oncol Clin N Am. October 2015; 24(4):765-777.
- The American Cancer Society provides information on Familial stomach cancer. Please click on the link to access this resource.
- Mayo Clinic has an information page on Familial stomach cancer.
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
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- PubMed is a searchable database of medical literature and lists journal articles that discuss Familial stomach cancer. Click on the link to view a sample search on this topic.