Platelet storage pool deficiency
Other Names for this Disease
- Platelet storage pool diseases
- Storage pool platelet disease
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platelet granules. Platelet granules are tiny storage sacs found within the platelets which release various substances to help stop bleeding. Platelet storage pool deficiencies occur when platelet granules are absent, reduced in number, or unable to empty their contents into the bloodstream. The signs and symptoms include frequent nosebleeds; abnormally heavy or prolonged menstruation; easy bruising; recurrent anemia; and abnormal bleeding after surgery, dental work or childbirth. Platelet storage pool deficiencies may be genetic or acquired (non-genetic). They can also be part of an inherited genetic syndrome such as Hermansky-Pudlak syndrome, Chediak-Higashi syndrome, thrombocytopenia-absent radius (TAR) syndrome, and Wiskott-Aldrich syndrome. Treatment is symptomatic.Platelet storage pool deficiency refers to a group of conditions that are caused by problems with the
Last updated: 4/14/2015
- Jewell, M., MaGann, EF, Barr, A., and Baker, R. Management of platelet storage pool deficiency during pregnancy. Australian and New Zealand Journal of Obstetrics and Gynecology. 2003; 43(2):171-172.
- Storage Pool Platelet Disease. Online Mendelian Inheritance of Man. March 3, 2009; http://omim.org/entry/185050. Accessed 7/30/2014.
- Riley RS. Platelet Storage Pool Diseases. Virginia Commonwealth University. http://www.pathology.vcu.edu/clinical/coag/SPD.pdf. Accessed 7/30/2014.
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- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
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