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Diseases

Genetic and Rare Diseases Information Center (GARD)

Hereditary neuropathy with liability to pressure palsy


Other Names for this Disease
  • Current pressure-sensitive neuropathy
  • Hereditary neuropathy with liability to pressure palsies
  • Heterozygous microdeletion 17p11.2p12
  • HNPP
  • Polyneuropathy, familial recurrent
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Your Question

What treatments are available for hereditary neuropathy with liability to pressure palsy?

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

What treatments are available for hereditary neuropathy with liability to pressure palsy?

There is no specific treatment for hereditary neuropathy with liability to pressure palsy. Treatment is based on an individual's symptoms. Some people with this condition use braces, such as a wrist splint or ankle-foot orthosis (AFO). Protective pads worn at the elbows or knees may prevent pressure and trauma to local nerves. Activities to avoid include prolonged sitting with legs crossed, occupations requiring repetitive movements of the wrist, prolonged leaning on elbows, and rapid weight loss. Vincristine, commonly used in the treatment of lymphoma, has been reported to worsen the symptoms of hereditary neuropathy with liability to pressure palsy. Surgical decompression of nerves remains a controversial treament for this condition.[1]

Last updated: 7/24/2015

References
Other Names for this Disease
  • Current pressure-sensitive neuropathy
  • Hereditary neuropathy with liability to pressure palsies
  • Heterozygous microdeletion 17p11.2p12
  • HNPP
  • Polyneuropathy, familial recurrent
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.