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Diseases

Genetic and Rare Diseases Information Center (GARD)

Tracheobronchopathia osteoplastica


Other Names for this Disease
  • Cartilaginous or bony projections into the tracheobronchial lumen
  • Tracheobronchopathia osteochondroplastica
  • Tracheopathia osteoplastica
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Overview

Tracheobronchopathia osteoplastica (TO) is a rare condition of the large airways. It is characterized by the presence of multiple growths (nodules) made of bone and cartilage tissue, in the submucosa of the tracheobronchial wall. The nodules protrude into the spaces inside the trachea and bronchi, which can lead to airway obstruction. Affected people may have persisting or recurrent respiratory symptoms, and/or recurrent infections. The cause of TO is not currently known. There is no specific treatment to prevent the formation of nodules. Laser therapy or removal of the nodules may be needed in some cases.[1]
Last updated: 9/8/2014

References

  1. Lazor R, Cordier JF. Tracheobronchopathia osteochondroplastica. Orphanet encyclopedia. June, 2004; https://www.orpha.net/data/patho/GB/uk-TO.pdf. Accessed 9/8/2014.
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In Depth Information

  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Tracheobronchopathia osteoplastica. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Cartilaginous or bony projections into the tracheobronchial lumen
  • Tracheobronchopathia osteochondroplastica
  • Tracheopathia osteoplastica
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.