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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Chromosome 3p duplication


Other Names for this Disease
  • 3p duplication
  • 3p trisomy
  • Duplication 3p
  • Partial trisomy 3p
  • Trisomy 3p
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Cause

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What causes chromosome 3p duplication?

People with chromosome 3p duplication have an extra (duplicate) copy of the genetic material located on the short arm (p) of chromosome 3 in each cell. The features associated with the condition vary significantly from person to person depending on the size and location of the duplication and which genes are involved.[1][2]

In some cases, this duplication is inherited from a parent with a balanced translocation. Other cases are considered "de novo" and occur sporadically as a random event when the egg or the sperm is made. There is nothing that a person can do to cause or prevent this duplication from happening.[1][2]
Last updated: 5/19/2015

References
  1. Han DH, Chang JY, Lee WI, Bae CW. A case of partial trisomy 3p syndrome with rare clinical manifestations. Korean J Pediatr. March 2012; 55(3):107-110.
  2. Natera-de Benito D, García-Pérez MA, Martínez-Granero MÁ, Izquierdo-López L.. A patient with a duplication of chromosome 3p (p24.1p26.2): a comparison with other partial 3p trisomies. Am J Med Genet A. 2014 Feb;164A(2):548-50. February 2014; 164A(2):548-550.


Other Names for this Disease
  • 3p duplication
  • 3p trisomy
  • Duplication 3p
  • Partial trisomy 3p
  • Trisomy 3p
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.