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Diseases

Genetic and Rare Diseases Information Center (GARD)

Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)


Other Names for this Disease
  • AML with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)
  • AML with inv(16)(p13.1q22) or t(16;16)(p13.1;q22)
  • CBFB-MYH11
  • Acute myelomonocytic leukemia
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Treatment

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How might acute myelomonocytic leukemia be treated?

Acute myelomonocytic leukemia (AMML) is typically treated with chemotherapy, drugs injected into the bloodstream that target and destroy cancer cells.  The amount and type of chemotherapy used to treat AMML depends on the age and health of the affected individual.  The first step of chemotherapy for AMML is induction therapy, treatment with drugs that aim to destroy the cancer cells in the bone marrow and blood.  Induction thearpy is followed by a rest phase to allow the affected individual to recover from the initial treatments.  Then, the second step of chemotherapy is given, called consolidation therapy, which should destroy any cancer cells that may remain in the body.[1]  Stem cell transplant or participation in a clinical trial may also be used to treat AMML if chemotherapy treatments are unsuccessful.[2]
Last updated: 2/12/2013

References
  1. American Cancer Society. Detailed Guide. Leukemia - Acute Myeloid (Myelogenous). January 2013; http://www.cancer.org/cancer/leukemia-acutemyeloidaml/detailedguide/index. Accessed 2/12/2013.
  2. National Comprehensive Cancer Network. Acute Myeloid Leukemia. NCCN Clinical Practice Guidelines in Oncology. 2013; http://www.nccn.org/professionals/physician_gls/pdf/aml.pdf.


Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) . Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
Other Names for this Disease
  • AML with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)
  • AML with inv(16)(p13.1q22) or t(16;16)(p13.1;q22)
  • CBFB-MYH11
  • Acute myelomonocytic leukemia
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.