Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Troyer syndrome


Other Names for this Disease
  • SPG20
  • Spastic paraparesis, childhood-onset, with distal muscle wasting
  • Spastic paraplegia, autosomal recessive, Troyer type
  • Autosomal recessive spastic paraplegia type 20
  • Spastic paraplegia 20, autosomal recessive
Related Diseases
  • Hereditary spastic paraplegia - autosomal recessive inheritance
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

Newline Maker

How might Troyer syndrome be treated?

There are currently no treatments known to prevent or slow the progression of Troyer syndrome.[1] Treatment aims to relieve symptoms of the disease and improve quality of life.

Treatment for spasticity involves both exercise and medication, especially baclofen (Lioresal®), which is used either orally or by intrathecal pump. Tizanidine, dantrolene (with precautions), and Botox® have also been useful in reducing muscle spasticity. Daily physical therapy is recommended.[2]

Treatment may also include:
  • Occupational therapy, assistive walking devices, and ankle-foot orthotics as needed
  • Oxybutynin to reduce urinary urgency
  • Antidepressants or mood stabilizers to manage emotional or mood disorders[2]

Additional information about the management of Troyer syndrome can be viewed on the GeneReviews Web site.

Last updated: 12/8/2015

References
  1. Troyer Syndrome Information Page. NINDS. January 3, 2012; http://www.ninds.nih.gov/disorders/troyer_syndrome/troyer_syndrome.htm.
  2. Patel H, Harlalka G & Crosby A. Troyer syndrome. GeneReviews. August 4, 2011; http://www.ncbi.nlm.nih.gov/books/NBK1382/.


GARD Video Tutorial

  • Finding Treatment Information - A video developed by GARD Information Specialists that explains how you can find information about treatment for a rare disease.

    Finding Treatment Information

Management Guidelines

  • GeneReviews provides current, expert-authored, peer-reviewed, full-text articles describing the application of genetic testing to the diagnosis, management, and genetic counseling of patients with specific inherited conditions.
Other Names for this Disease
  • SPG20
  • Spastic paraparesis, childhood-onset, with distal muscle wasting
  • Spastic paraplegia, autosomal recessive, Troyer type
  • Autosomal recessive spastic paraplegia type 20
  • Spastic paraplegia 20, autosomal recessive
Related Diseases
  • Hereditary spastic paraplegia - autosomal recessive inheritance
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.