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Diseases

Genetic and Rare Diseases Information Center (GARD)

Acute promyelocytic leukemia


Other Names for this Disease
  • Acute myeloblastic leukemia type 3
  • Acute myeloid leukemia with t(15;17)(q22;q12);(PML/RARalpha) and variants
  • AML M3
  • AML with t(15;17)(q22;q12);(PML/RARalpha) and variants
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Tests & Diagnosis

Newline Maker

Is predictive genetic testing available for acute promyelocytic leukemia?

We were unable to locate information about the availability of predictive testing for acute promyelocytic leukemia (APL). Predictive genetic testing is primarily an option for individuals at risk for inherited cancers and other inherited disorders; APL is not an inherited cancer. Predictive genetic tests are generally available if a close family member has had a genetic test which has identified a specific mutation that is associated with an inherited predisposition to cancer.[1] APL is caused by a somatic mutation which is acquired during a person's lifetime and is not passed on to children. Furthermore, it is not necessarily known when during a person's lifetime a somatic mutation might occur.

Individuals that are interested in learning more about predictive testing for a particular type of cancer should speak with a genetics professional.
Last updated: 2/6/2012

References
  1. Predictive Testing for Inherited Cancer. Genetic Interest Group. March 2009; http://www.geneticalliance.org.uk/docs/inheritedcancer.pdf. Accessed 2/6/2012.


Testing

  • The Genetic Testing Registry (GTR) provides information about the genetic tests for this condition. The intended audience for the GTR is health care providers and researchers. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.
Other Names for this Disease
  • Acute myeloblastic leukemia type 3
  • Acute myeloid leukemia with t(15;17)(q22;q12);(PML/RARalpha) and variants
  • AML M3
  • AML with t(15;17)(q22;q12);(PML/RARalpha) and variants
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.