Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Uncombable hair syndrome


Other Names for this Disease
  • Pili trianguli et Canaliculi
  • Cheveux incoiffables
  • Unmanageable hair syndrome
  • Spun glass hair
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Uncombable hair syndrome (UHS) is a rare disorder of the hair shaft of the scalp. It usually is characterized by silvery-blond or straw-colored hair that is disorderly; stands out from the scalp; and cannot be combed flat. It may first become apparent from 3 months of age to 12 years of age.[1] UHS is likely inherited in an autosomal dominant manner with reduced penetrance. A responsible gene has not yet been identified.[2][3] The condition often spontaneously regresses in late childhood.[3]
Last updated: 2/17/2016

References

  1. Ralph Trüeb. Uncombable hair syndrome. Orphanet Encyclopedia. September 2003; http://www.orpha.net/data/patho/GB/uk-uncombable.pdf.
  2. Carol A. Bocchini. Uncombable hair syndrome. OMIM. April 5, 2011; http://www.omim.org/entry/191480.
  3. Alexander Navarini. Uncombable hair syndrome. Orphanet. January, 2012; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=1410.
GARD Video Tutorials
GARD Video Tutorials
Learn how to find information on treatment, research, specialists, and more.
Your Questions Answered
Your Questions Answered
View questions about this condition answered by GARD Information Specialists. You can also submit a new question.

Basic Information

  • DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
    Orphanet
    Orphanet
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Uncombable hair syndrome. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Pili trianguli et Canaliculi
  • Cheveux incoiffables
  • Unmanageable hair syndrome
  • Spun glass hair
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.