Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Mayer-Rokitansky-Kuster-Hauser syndrome


Other Names for this Disease
  • RKH syndrome
  • Von Mayer Rokitansky Kuster anomaly
  • Mayer Rokitansky Kuster Hauser syndrome
  • Congenital absence of the uterus and vagina
  • Uterus bipartitus solidus rudimentarius cum vagina solida
Related Diseases
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Cause

Newline Maker

What causes Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome?

The exact cause of MRKH syndrome is not known. It is thought to be multifactorial, due to a combination of genetic and environmental factors. However, researchers have not yet identified any genes associated with the disorder.[1]

The specific reproductive features of MRKH syndrome are due to incomplete development of the Müllerian ducts. These ducts are present in the embryo and give rise to the fallopian tubes, uterus, cervix, and upper portion of the vagina. It is unclear why some affected women have abnormalities in other parts of the body.[1]

Last updated: 4/15/2015

References
  1. Mayer-Rokitansky-Küster-Hauser syndrome. Genetics Home Reference. March, 2015; http://ghr.nlm.nih.gov/condition/mayer-rokitansky-kuster-hauser-syndrome.


Other Names for this Disease
  • RKH syndrome
  • Von Mayer Rokitansky Kuster anomaly
  • Mayer Rokitansky Kuster Hauser syndrome
  • Congenital absence of the uterus and vagina
  • Uterus bipartitus solidus rudimentarius cum vagina solida
Related Diseases
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.