Other Names for this Disease
- Willi-Prader syndrome
- Prader-Labhart-Willi syndrome
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Your QuestionMy foster child will be tested for Prader-Willi syndrome, but has a very high IQ. Is it possible for people with Prader-Willi to have high IQs?
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Most people with Prader-Willi syndrome (PWS) have mild to moderate intellectual impairment and learning disabilities.  One study found that people with PWS have a range of IQs with an overall average IQ of 60, which is 40 points lower than in the general population. Some people with PWS have an IQ that is within the average range; there have been reports of affected people with IQs of 103 and 105. However, even with an IQ in the average range, a person with PWS may have a lack of understanding for abstract concepts, and may still experience difficulty relating to peers. We were not able to find any published case reports or studies, however, reporting a person with PWS in the above average range.
Last updated: 7/7/2016
- Prader-Willi syndrome. Genetics Home Reference. June 2014; https://ghr.nlm.nih.gov/condition/prader-willi-syndrome#.
- Eunice Kennedy Shriver National Institute of Child & Human Development. Prader-Willi syndrome. Eunice Kennedy Shriver National Institute of Child & Human Development. January 14 2014; https://www.nichd.nih.gov/health/topics/prader-willi/Pages/default.aspx.
- Whittington J, Holland A, Webb T, Butler J, Clark D, and Boer H. Academic underachievement by people with Prader-Willi syndrome. J Intellect Disabil Res. February 2004; 48(Pt2):188-200. http://www.ncbi.nlm.nih.gov/pubmed/14723660.
- Whittington J, Holland A, and Webb T. Relationship between the IQ of people with Prader-Willi syndrome and that of their siblings: evidence for imprinted gene effects. J Intellect Disabil Res. May 2009; 53(5):411-18. http://www.ncbi.nlm.nih.gov/pubmed/19207281.
- Whittington J and Holland A. Neurobehavioral phenotype in Prader-Willi syndrome. Am J Med Genet C Semin Med Genet. November 2010; 154c(4):438-47. http://www.ncbi.nlm.nih.gov/pubmed/20981773.