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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Achalasia


Other Names for this Disease
  • Achalasia cardia
  • Esophageal achalasia
  • Idiopathic achalasia
  • Idiopathic achalasia of esophagus
  • Primary achalasia
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Overview

Achalasia is a disorder of the esophagus, the tube that carries food from the mouth to the stomach.[1] It is characterized by enlargement of the esophagus, impaired ability of the esophagus to push food down toward the stomach (peristalsis), and failure of the ring-shaped muscle at the bottom of the esophagus (the lower esophageal sphincter) to relax.[2] Achalasia is caused by damage to the nerves of the esophagus. Treatment is aimed at reducing the pressure at the lower esophageal sphincter and may include Botox, medications, or surgery.[1]
Last updated: 7/20/2011

References

  1. Dugdale DC, Longstreth GF. Achalasia. MedlinePlus. January 10, 2010; http://www.nlm.nih.gov/medlineplus/ency/article/000267.htm. Accessed 7/20/2011.
  2. Achalasia. National Organization for Rare Disorders (NORD). 2007; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/118/viewAbstract. Accessed 7/20/2011.
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Basic Information

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
    Esophageal Motility Disorders
    Achalasia Imaging
  • The Merck Manual for health care professionals provides information on Achalasia.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Achalasia. Click on the link to view a sample search on this topic.
  • UpToDate has an article on Achalasia. Click on UpToDate to view the page.
Other Names for this Disease
  • Achalasia cardia
  • Esophageal achalasia
  • Idiopathic achalasia
  • Idiopathic achalasia of esophagus
  • Primary achalasia
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.