Acute intermittent porphyria
Other Names for this Disease
- Porphobilinogen deaminase deficiency
- PBGD deficiency
- Uroporphyrinogen synthase deficiency
- UPS deficiency
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porphyrias. AIP is caused by low levels of porphobilinogen deaminase (PBGD), an enzyme also often called hydroxymethylbilane synthase. The low levels of PBGD are generally not sufficient to cause symptoms; however, activating factors such as hormones, drugs, and dietary changes may trigger symptoms. Although most individuals with AIP never develop symptoms, symptomatic individuals typically present with abdominal pain with nausea. Treatment is dependent on the symptoms.Acute intermittent porphyria (AIP) is one of the liver (hepatic)
Last updated: 11/11/2015
- Acute Intermittent Porphyria (AIP). American Porphyria Foundation. 2015; http://www.porphyriafoundation.com/about-porphyria/types-of-porphyria/AIP. Accessed 11/11/2015.
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