Other Names for this Disease
- Dercum disease
- Dercum's disease
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Management of adiposis dolorosa is difficult and no currently available treatments have led to long-lasting, complete pain reduction. Surgical removal of particularly burdensome lesions and/or liposuction may be helpful for some people. However, lipomas have been known to reoccur and even increase in number at the same site or a nearby location. Weight reduction may help with joint pain in some individuals, but has proven to be difficult to achieve and generally doesn't offer significant relief of symptoms. There is currently no drug known to change the course of the disease. Available treatments mainly focus on alleviating symptoms and may include:
- prednisone or intravenous lidocaine for pain
- traditional pain medicines such nonsteroidal anti-inflammatory drugs (which are often ineffective), or acetaminophen combined with an opioid analgesic
- a cortisone/anesthetic injection for localized pain
- diuretics for swelling of the fingers
Last updated: 6/28/2016
- Hansson E, Svensson H, Brorson H. Review of Dercum's disease and proposal of diagnostic criteria, diagnostic methods, classification and management.. Orphanet Journal of Rare Diseases. 2012; 7:23. http://ojrd.biomedcentral.com/articles/10.1186/1750-1172-7-23.
- Dercum's Disease (DD). Fat Disorders Research Society. http://www.fatdisorders.org/fat-disorders/dercums-description.
- Laura F McGevna. Adiposis Dolorosa. Medscape Reference. February 6, 2015; http://emedicine.medscape.com/article/1082083-treatment.
- The Centers for Mendelian Genomics program is working to discover the causes of rare genetic disorders. For more information about applying to the research study, please visit their website.