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Diseases

Genetic and Rare Diseases Information Center (GARD)

Adiposis dolorosa


Other Names for this Disease
  • Dercum disease
  • Dercum's disease
  • Adiposalgia
  • Adipose tissue rheumatism
  • Dercums disease
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Inheritance

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Is adiposis dolorosa inherited?

Most cases of adiposis dolorosa are sporadic (not inherited). This means that it usually occurs in people with no family history of the condition. Adiposis dolorosa has rarely been reported to occur in more than one family member. In some of these cases, it appears to have been inherited in an autosomal dominant manner.[1][2] In these cases, when an affected person has children, each child has a 50% (1 in 2) risk to inherit the gene causing the condition. However, no associated genes have been identified.[1][2]
Last updated: 2/4/2016

References
  1. Learning About Dercum Disease. NHGRI. June 27, 2012; http://www.genome.gov/17516629.
  2. Adiposis dolorosa. Genetics Home Reference. July, 2012; http://ghr.nlm.nih.gov/condition/adiposis-dolorosa.


Other Names for this Disease
  • Dercum disease
  • Dercum's disease
  • Adiposalgia
  • Adipose tissue rheumatism
  • Dercums disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.