Other Names for this Disease
- Alexanders leukodystrophy
- Megalencephaly in infancy accompanied by progressive spasticity and dementia
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No specific therapy is currently available for Alexander disease.Management is supportive and includes attention to general care, physical and occupational therapy, nutritional requirements, antibiotic treatment for any infection, and antiepileptic drugs (AED) for seizure control.
Last updated: 10/31/2015
- Gorospe JR. Alexander Disease. GeneReviews. January 8, 2015; http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=alexander. Accessed 10/31/2015.
- Finding Treatment Information - A video developed by GARD Information Specialists that explains how you can find information about treatment for a rare disease.
- GeneReviews provides current, expert-authored, peer-reviewed, full-text articles describing the application of genetic testing to the diagnosis, management, and genetic counseling of patients with specific inherited conditions. Click on the link to view the article on this topic.
- Johnson CP, Kastner TA. Helping families raise children with special health care needs at home. Pediatrics. 2005; 115(2):507-511.