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Diseases

Genetic and Rare Diseases Information Center (GARD)

Alexander disease


Other Names for this Disease
  • Alexanders leukodystrophy
  • Megalencephaly in infancy accompanied by progressive spasticity and dementia
  • AxD
Related Diseases
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Your Question

How many people are affected by Alexander disease? 

Our Answer

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How many people are affected by Alexander disease?

The exact prevalence of Alexander disease is unknown. It is estimated to occur in about 1 in 1 million births.[1] Since the description of the first person with Alexander Disease in 1949, no more than 550 cases have been reported.[2][3] GFAP mutations have been confirmed in 189 reported individuals.[3]
Last updated: 1/11/2016

References
Other Names for this Disease
  • Alexanders leukodystrophy
  • Megalencephaly in infancy accompanied by progressive spasticity and dementia
  • AxD
Related Diseases
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.