Other Names for this Disease
- Alexanders leukodystrophy
- Megalencephaly in infancy accompanied by progressive spasticity and dementia
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The exact prevalence of Alexander disease is unknown. It is estimated to occur in about 1 in 1 million births. Since the description of the first in 1949, no more than 550 cases have been reported. GFAP have been confirmed in 189 reported individuals.
Last updated: 1/11/2016
- Alexander Disease. National Organization for Rare Disorders (NORD): National Organization for Rare Disorders (NORD); http://rarediseases.org/rare-diseases/alexander-disease/. Accessed 1/11/2016.
- Alexander disease. Genetics Home Reference. October, 2015; http://ghr.nlm.nih.gov/condition=alexanderdisease. Accessed 10/31/2015.
- Gorospe JR. Alexander Disease. GeneReviews. January 8, 2015; http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=alexander. Accessed 10/31/2015.