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Diseases

Genetic and Rare Diseases Information Center (GARD)

Alexander disease


Other Names for this Disease
  • Alexanders leukodystrophy
  • Megalencephaly in infancy accompanied by progressive spasticity and dementia
Related Diseases
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Treatment

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What treatment is available for Alexander disease?

No specific therapy is currently available for Alexander disease. Management is supportive and includes attention to general care, physical and occupational therapy, nutritional requirements, antibiotic treatment for any infection, and antiepileptic drugs (AED) for seizure control.[1]

Physical and occupational therapy and speech therapy may be recommended depending on the specific signs and symptoms present. Physical and occupational therapy may be indicated in people with developmental and language delays.
Last updated: 12/29/2015

References
  1. Gorospe JR. Alexander Disease. GeneReviews. January 8, 2015; http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=alexander. Accessed 10/31/2015.


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Management Guidelines

Other Names for this Disease
  • Alexanders leukodystrophy
  • Megalencephaly in infancy accompanied by progressive spasticity and dementia
Related Diseases
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.