- Amyloidosis AL
- Amyloidosis primary systemic
- Light chain amyloidosis
- Localized AL amyloidosis
- Localized immunoglobulinic amyloidosis
Amyloidosis refers to a group of disorders in which protein fibers are deposited in tissues and organs, harming them. AL amyloidosis, also known as primary systemic amyloidosis, is the most common form of amyloidosis. It refers specifically to cases of amyloidosis where the deposits contain bits of immunoglobulin light chain. Signs and symptoms depend on the organs affected by the deposits, which may include the tongue, intestines, skeletal and smooth muscles, joints, nerves, skin, ligaments, heart, liver, spleen, and kidneys. AL amyloidosis is related to the plasma cell disorder multiple myeloma. Treatment may include chemotherapy directed at the abnormal plasma cells or stem cell transplantation.
- Dugdale DC. Primary amyloidosis. MedlinePlus. 2011; http://www.nlm.nih.gov/medlineplus/ency/article/000533.htm. Accessed 10/8/2012.
- Amyloidosis. MayoClinic. 2011; http://www.mayoclinic.com/health/amyloidosis/DS00431/METHOD=print&DSECTION=all. Accessed 10/8/2012.
- Urbancek S, Gascon P, Schwartz RA, Jacobson DR, Buxbaum J, Bogdan CA. Immunoglobulin-Related Amyloidosis . Medscape Reference. 2012; http://emedicine.medscape.com/article/208839-overview. Accessed 10/8/2012.
- Primary AL. Amyloidosis Foundation. 2011; http://www.amyloidosis.org/TreatmentInformation/primaryAL.html. Accessed 10/8/2012.
- The Mayo Clinic provides information on the diagnosis and treatment of amyloidosis.
- Amyloidosis Awareness is an illustrated booklet for patients and physicians developed by Amyloidosis Support Groups Inc. Versions of the booklet are also available in Spanish and Portuguese.
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
- The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC), part of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), conducts and supports research on a broad spectrum of diseases affecting public health. Click on the link to view information on this topic.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
Primary Systemic Amyloidosis
- PubMed is a searchable database of medical literature and lists journal articles that discuss AL amyloidosis. Click on the link to view a sample search on this topic.