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Diseases

Genetic and Rare Diseases Information Center (GARD)

Binswanger's disease


Other Names for this Disease
  • Dementia multi-infarct
  • Multi-infarct dementia
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Overview

Binswanger's disease is a type of dementia caused by widespread, microscopic areas of damage to the deep layers of white matter in the brain.[1] Most affected people experience progressive memory loss and deterioration of intellectual abilities (dementia); urinary urgency or incontinence; and an abnormally slow, unsteady gait (style of walking).[2] While there is no cure, the progression of Binswanger's disease can be slowed with healthy lifestyle choices. Treatment is based on the signs and symptoms present in each person.[1]
Last updated: 10/8/2015

References

  1. NINDS Binswanger's Disease Information Page. National Institute of Neurological Disorders and Stroke (NINDS). April 2015; http://www.ninds.nih.gov/disorders/binswangers/binswangers.htm.
  2. Elble RJ. Binswanger's Disease. National Organization for Rare Disorders. 2012; http://rarediseases.org/rare-diseases/binswangers-disease/.
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Basic Information

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Binswanger's disease. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Dementia multi-infarct
  • Multi-infarct dementia
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.