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Diseases

Genetic and Rare Diseases Information Center (GARD)

Budd-Chiari syndrome


Other Names for this Disease
  • Membranous obstruction of the inferior vena cava
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Treatment

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How might Budd-Chiari syndrome be treated?

The treatment of Budd-Chiari syndrome varies, depending on the cause of the blockage. Medical treatments may include:[1]
  • Blood-thinning (anticoagulation) medications
  • Clot-busting drugs (thrombolytic treatment)
  • Treatment for the liver disease, including ascites

Surgical treatments may also be considered and include:[1]

  • Angioplasty and stent placement
  • Transjugular intrahepatic portosystemic shunt (TIPS)
  • Venous shunt surgery

While medical therapy can be instituted for short-term, symptomatic benefit, medical therapy alone has been associated with a high 2-year mortality rate (80-85%).[2]

In cases of severe cirrhosis liver transplant may be needed.[2] You can view more detailed information regarding the medical and surgical options for treatment of Budd-Chiari syndrome by visiting the Medscape Reference website on Budd-Chiari syndrome treatment & managment. You may need to register to view the article, but registration is free.

Last updated: 5/2/2016

References
  1. Hepatic vein obstruction (Budd-Chiari). MedlinePlus. 2014; http://www.nlm.nih.gov/medlineplus/ency/article/000239.htm.
  2. Roy PK, Choudhary A, Shojamanesh H, Bragg J, Dehadrai G, Bashir S. Budd-Chiari Syndrome: Treatment & Medication. Medscape Reference. 2015; http://emedicine.medscape.com/article/184430-treatment.


Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Budd-Chiari syndrome. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
Other Names for this Disease
  • Membranous obstruction of the inferior vena cava
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.