Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Print friendly version

Buerger disease


Other Names for this Disease
  • Buerger's disease
  • Inflammatory occlusive peripheral vascular disease
  • Occlusive peripheral vascular disease
  • TAO
  • Thromboangiitis obliterans
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

Newline Maker

How is Buerger disease treated?

Currently there is not a cure for Buerger disease, however there are treatments that can help control it. The most essential part of treatment is to avoid all tobacco and nicotine products.[1][2][3] Even one cigarette a day can worsen the disease.[1] A doctor can help a person with Buerger disease learn about safe medications and programs to combat smoking/nicotine addiction. Continued smoking is associated with an overall amputation rate of 40 to 50 percent.[3]

The following treatments may also be helpful, but do not replace smoking/nicotine cessation:[2][1][3]

Medications to dilate blood vessels and improve blood flow (e.g., intravenous Iloprost)
Medications to dissolve blood clots
Treatment with calcium channel blockers
Walking exercises
Intermittent compression of the arms and legs to increase blood flow to your extremities
Surgical sympathectomy (a controversial surgery to cut the nerves to the affected area to control pain and increase blood flow)
Therapeutic angiogenesis (medications to stimulate growth of new blood vessels)
Spinal cord stimulation
Amputation, if infection or gangrene occurs
Last updated: 6/16/2015

References
  1. Ferri F. Thromboangiitis obliterans. In: Goldman-Cecil Medicine. Ferri's Clinical Advisor 2016. Philadelphia, PA: Elsevier, Inc; 2016; Accessed 6/16/2015.
  2. Buerger's disease. MayoClinic. February 1, 2013; http://www.mayoclinic.org/diseases-conditions/buergers-disease/basics/definition/con-20029501?METHOD=print. Accessed 6/16/2015.
  3. Mohler ER, Olin JW. Thromboangiitis obliterans (Buerger's disease). In: Hunder GG, Eidt J, Mills JL eds. UpToDate. Waltham, MA: UpToDate; 2015; Accessed 6/16/2015.


GARD Video Tutorial

  • Finding Treatment Information - A video developed by GARD Information Specialists that explains how you can find information about treatment for a rare disease.

    Finding Treatment Information

Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Buerger disease. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
Other Names for this Disease
  • Buerger's disease
  • Inflammatory occlusive peripheral vascular disease
  • Occlusive peripheral vascular disease
  • TAO
  • Thromboangiitis obliterans
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.