Unicentric Castleman disease
Other Names for this Disease
- Unicentric angiofollicular ganglionic hyperplasia
- Unicentric angiofollicular lymph hyperplasia
- Localized Castleman disease
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lymph nodes and related tissues. It is a form of Castleman disease that is "localized" to a single set of lymph nodes (as opposed to multicentric Castleman disease which has more widespread effects). UCD often starts as an enlarged lymph node. Depending on the location of this enlarged node, some people will have no additional features of the condition, while others will develop symptoms when it pushes on nearby organs and/or tissues. The exact underlying cause of UCD is currently unknown. Treatment typically includes surgical removal of the affected lymph node.Unicentric Castleman disease (UCD) is a rare condition that affects the
Last updated: 6/24/2015
- Castleman Disease. American Cancer Society. July 2014; http://www.cancer.org/cancer/castlemandisease/detailedguide/index.
- Jennifer R Brown, MD, PhD; Jon C Aster, MD; Nikhil C Munshi, MD. Unicentric Castleman's disease. UpToDate. November 2013; Accessed 6/24/2015.
- Neetu Radhakrishnan, MD. Castleman Disease. Medscape Reference. January 2015; http://emedicine.medscape.com/article/2219018-overview.
- The American Cancer Society provides detailed information about Unicentric Castleman disease. Click on the link to access this information.
- MayoClinic.com provides an information page for this topic. Click on the link to view this information.
- The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Unicentric Castleman disease. Click on the link to view a sample search on this topic.