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Diseases

Genetic and Rare Diseases Information Center (GARD)

Cholera


Other Names for this Disease
  • Vibrio cholerae infection
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Overview

Cholera is an infection of the small intestines that is caused by the bacterium Vibrio cholera. The condition can range from mild to severe and many affected people may have no obvious signs or symptoms. Approximately 5-10% of infected people will have severe disease with watery diarrhea and vomiting leading to rapid fluid loss, dehydration, and shock. If left untreated, this can cause acute renal failure, severe electrolyte imbalances, coma, or even death. People develop cholera when they eat food or drink water that is contaminated with Vibrio cholera. The condition occurs most often in places that lack water treatment and have poor sanitation and inadequate hygiene. Treatment aims to prevent dehydration and replace the fluids and salts that are lost through diarrhea.[1][2][3]
Last updated: 4/7/2016

References

  1. Sajeev Handa, MBBCh, BAO, LRCSI, LRCPI. Cholera. Medscape Reference. February 2016; http://emedicine.medscape.com/article/962643-overview.
  2. Cholera. MedlinePlus. May 2014; https://www.nlm.nih.gov/medlineplus/ency/article/000303.htm.
  3. Cholera - Vibrio cholerae infection. Centers for Disease Control and Prevention. October 2014; http://www.cdc.gov/cholera/index.html.
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Basic Information

  • You can obtain information on this topic from the Centers for Disease Control and Prevention (CDC). The CDC is recognized as the lead federal agency for developing and applying disease prevention and control, environmental health, and health promotion and education activities designed to improve the health of the people of the United States.
  • Mayo Clinic has an information page on Cholera.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • MeSH® (Medical Subject Headings) is a terminology tool used by the National Library of Medicine. Click on the link to view information on this topic.
  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Cholera. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Vibrio cholerae infection
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.