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Diseases

Genetic and Rare Diseases Information Center (GARD)

Chronic inflammatory demyelinating polyneuropathy


Other Names for this Disease
  • CIDP
  • Chronic Inflammatory Demyelinating Polyradiculoneuropathy
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Prognosis

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What is the long-term outlook for people with chronic inflammatory demyelinating polyneuropathy (CIDP)?

Data are limited regarding the long-term outlook (prognosis) of CIDP,[1] and the course and prognosis appear to vary among affected people.[2] Some may have a "bout" of CIDP followed by spontaneous recovery, while others may have many bouts with partial recovery in between relapses. Some people are left with residual numbness or weakness that can lead to reduced quality of life.[2][3] Complete remission, partial remission, and severe disability have all been documented.[1] Quadriplegia, respiratory failure and death can occur, but are rare.[3]

It has been reported that approximately two-thirds of people with CIDP will initially respond to any single standard therapy (intravenous immune globulin, glucocorticoid, and plasma exchange), while about 10 to 15 percent are resistant to all of these.[1]
Last updated: 11/23/2015

References
  1. Richard A Lewis. Chronic inflammatory demyelinating polyneuropathy: Treatment and prognosis. UpToDate. Waltham, MA: UpToDate; October, 2015;
  2. NINDS Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Information Page. NINDS. November 6, 2015; http://www.ninds.nih.gov/disorders/cidp/cidp.htm.
  3. Jean-Michel Vallat. Chronic inflammatory demyelinating polyneuropathy. Orphanet. December, 2010; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=2932.


Other Names for this Disease
  • CIDP
  • Chronic Inflammatory Demyelinating Polyradiculoneuropathy
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.