Chronic recurrent multifocal osteomyelitis
Other Names for this Disease
- Multifocal osteomyelitis, chronic
- Chronic multifocal osteomyelitis
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Your QuestionMy son was diagnosed 2 years ago. At first he was doing good on his pain medication, but now he needs medicine before he can even get up as he can't move. Is there anything else that can treat his pain?
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Due to the rare nature of the condition, there is limited data regarding the best treatment approach for people with chronic recurrent multifocal osteomyelitis (CRMO). When CRMO occurs along with psoriasis or inflammatory bowel disease the goal is to treat both the CRMO as well as the skin and gastrointestinal symptoms. In this situation, treatment with a TNF inhibitor may be recommended. Initial treatment of isolated CRMO often involves NSAIDs. If NSAIDs are unable to control pain, additional treatment options include antirheumatic drugs (e.g., corticosteroids, methotrexate, sulfasalazine, colchicine, and azithromycin), TNF inhibitors, or bisphosphonates.
Last updated: 5/15/2013
- Ferguson PJ, Sandu M. Current understanding of the pathogenesis and management of chronic recurrent multifocal osteomyelitis. Curr Rheumatol Rep. 2012 Apr;14(2):130-41; http://www.ncbi.nlm.nih.gov/pubmed/?term=22359228. Accessed 5/15/2013.