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Diseases

Genetic and Rare Diseases Information Center (GARD)

Eosinophilic granulomatosis with polyangiitis


Other Names for this Disease
  • CSS
  • Allergic granulomatous and angiitis
  • Allergic angiitis and granulomatosis
  • Allergic granulomatosis
  • Churg-Strauss vasculitis
Related Diseases
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Overview

Churg Strauss syndrome is a condition characterized by asthma, high levels of eosinophils (a type of white blood cell that helps fight infection), and inflammation of small to medium sized blood vessels (vasculitis). The inflamed vessels can affect various organ systems including the lungs, gastrointestinal tract, skin, heart and nervous system. The exact cause of Churg Strauss syndrome is unknown, but it is thought to be an autoimmune disorder. Treatment may involve the use of glucocorticoids and/or other immunosuppressive therapies.[1][2][3]
Last updated: 3/9/2015

References

  1. Book W. Information About Chirg Strauss Syndrome. American Partnership for Eosinophilic Disorders. 2005; http://www.apfed.org/css.htm. Accessed 4/4/2011.
  2. What is Churg Strauss Syndrome?. Churg Strauss Syndrome Association. 2006; http://www.cssassociation.org/what-is-churg-strauss-syndrome.html. Accessed 4/4/2011.
  3. Wolfgang Gross and Bernhard Hellmich. Eosinophilic granulomatosis with polyangiitis. Orphanet. November, 2014; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=183. Accessed 3/9/2015.
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Basic Information

  • Read a "What is Churg Strauss syndrome? factsheet by the Churg Strauss Syndrome Association.
  • DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
  • The Mayo Clinic Web site provides further information on Eosinophilic granulomatosis with polyangiitis.
  • The Merck Manuals Online Medical Library provides information on this condition for patients and caregivers. 
  • The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Eosinophilic granulomatosis with polyangiitis. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • CSS
  • Allergic granulomatous and angiitis
  • Allergic angiitis and granulomatosis
  • Allergic granulomatosis
  • Churg-Strauss vasculitis
Related Diseases
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.