- Cockayne's syndrome
- Dwarfism-retinal atrophy-deafness syndrome
- Progeria-like syndrome
- Progeroid nanism
Your QuestionI have a friend whose toddler son was diagnosed with Cockayne syndrome. I would really like some more information about this condition and the survival rate for his son.
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The prognosis for Cockayne syndrome varies by the disease type. There are three types of Cockayne syndrome:
Cockayne Syndrome Type 1 (type A) is marked by normal development until a child is 1 or 2 years old, at which point growth slows and developmental delays are noticed. Life expectancy for type 1 is approximately 10 to 20 years.Cockayne syndrome type 2 (type B), also known as cerebro-oculo-facio-skeletal (COFS) and Pena-Shokeir syndrome type II, has severe symptoms present at birth and normal brain development stops after birth. Average lifespan for children with type 2 is up to 7 years of age.
Cockayne syndrome type 3 (type C) appears later in childhood with milder symptoms than the other types and a slower progression of the disorder. Individuals with this type of Cockayne syndrome live into adulthood, with an average lifespan of 40 to 50 years.
- Cockayne Syndrome Brochure. Share & Care Cockayne Syndrome Network. 2008; http://cockaynesyndrome.net/main/AboutCS.aspx. Accessed 4/17/2015.
- Genetics Home Reference. Cockayne Syndrome. May 2010; http://ghr.nlm.nih.gov/condition/cockayne-syndrome. Accessed 4/17/2015.
- Vincent Laugel, MD, PhD. Cockayne Syndrome. Gene Reviews. June 14, 2012; http://www.ncbi.nlm.nih.gov/books/NBK1342/. Accessed 4/17/2015.